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The goal of this slow progression is to allow the body to adjust to the compounds effects on appetite regulation, gastric emptying, and metabolic signaling while minimizing gastrointestinal discomfort and other tolerability concerns
Otsuki, Y
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A 2025 human pilot study reported no adverse cardiac, hepatic, or renal effects at IV doses of 10-20mg
Chapter 13 Exploration of biotechnological studies in low-calorie sweetener Stevia rebaudiana : present and future prospects, in Medicinal and Aromatic Plants: Expanding Their Horizons Through Omics
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