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Therapies that receive FDA accelerated approval based on surrogate markers are expected to undergo further testing to confirm clinical benefits, and the agency can rescind approval if they fail to measure up

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Corboz MR et al (2008): Mechanism of decongestant activity of 2-adrenoceptor agonists

GSH also protects the cell from xenobiotics and heavy metals through the formation of GSH S-conjugates and their subsequent export in the vacuole or directly out of the cell

Note that the potential benefits of garlic consumption/supplementation on cardiovascular health may also be attributed to antioxidant and anti-inflammatory activities described above