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Certain situations make it a reasonable, and sometimes preferable, option

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SGLT2 inhibitors are one of the recommended "add-on" therapies to metformin in the current ADA diabetes mellitus type 2 guidelines (alongside sulfonylureas, TZDs, DPP-4 inhibitors, GLP-1 agonists, or insulin) and the guidelines make no preference for any particular class, leaving it to patient-specific factors

Semaglutide itself does not cause muscle loss

360 Wellness prescribes injectable and oral semaglutide after thorough metabolic evaluation