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[7] However, the use of GLP-1 agonists during pregnancy and lactation is less well understood, as these groups are typically excluded from clinical trials

This trial is for adults who have been unsuccessful in past dieting efforts, are overweight or obese with a BMI 27, and suffer from knee pain due to osteoarthritis

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In this context, it is necessary, in addition, to have an adapted nutritional management characterized in particular by a high protein intake and regular resistance physical activity, i.e., weight training/muscle strengthening