semaglutide and cardiovascular outcomes in patients with type 2 diabetes Oral Patients with type 2 #diabetes

Key properties: Strong appetite stimulation the most pronounced of any GHRP (can be a benefit or drawback) Moderate cortisol increase higher than GHRP-2 Good GH release effective but not as potent per mcg as GHRP-2 Strongest ghrelin mimicry most activation of non-GH ghrelin pathways GHRP-6 is studied when appetite stimulation is a desired effect (e.g., recovery from illness, muscle gain phases) alongside GH release

Some patients achieve adequate glycaemic control at submaximal doses with better tolerability

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Key takeaways: Glucagon-like peptide-1 (GLP-1) injections such as Wegovy (semaglutide) and Zepbound (tirzepatide) are the most effective weight-loss medications available today

But key details remain unclear, Dusetzina said