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Drugs with glucagon-like peptide-1 receptor agonist (arGLP-1) action for overweight/obesity, such as liraglutide, semaglutide, and tirzepatide, have shown improvements in weight and body composition, as well as in parameters related to glucose metabolism, hypertension, dyslipidemia (reduction of triglycerides and increase in HDL cholesterol), and metabolic dysfunction-associated steatotic liver disease

It's a common pitfall

Frequently Asked Questions Are muscle cramps on semaglutide a sign that the medication isn't working

Suboptimal Treatment Response with AOMs Once a treatment has been initiated, it is important to consider what to do in the event of a suboptimal treatment response

Diabetes Technol Ther 14:67, 2012 89