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Nor were there any significant differences detected within groups between the initial and post-treatment assessments

Pediatr.Res 1982;16(2):89-91

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Empagliflozin resulted in reductions in incident or worsening nephropathy, a doubling of serum creatinine levels and renal replacement therapy in a pre-specified analysis of the EMPA-REG trial.52 Likewise, the results of the CANVAS study showed a possible benefit of canagliflozin in terms of the progression of albuminuria and a composite endpoint that included a sustained 40% reduction in GFR, the need for renal replacement therapy, or death due to renal causes.50 In contrast to the results previously reported with liraglutide, those afforded by the SGLT2 inhibitors included robust targets