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Compared with their SPF counterparts, young GF mice exhibit reduced thymus sizes and decreased numbers of lymphocytes, indicating a critical role for the microbiota in conventional T-cell development [57, 58]
The characteristics of all the subjects are presented as numbers (percentages) for categorical variables, as means standard deviations for parametrically distributed variables or as medians (interquartile ranges) for non-parametrically distributed variables
It is important to note that only the work of Adair (2001) evaluated oxidative status before and after NAC intervention, and the results showed no differences in the levels of glutathione peroxidase, GSH and thiobarbiturate reactive substances (TBARS), which may be related to the low prescribed dose of 50 mg/kg per day [39]