The Endocrine Society's 2017 clinical practice guideline on testosterone therapy in men with hypogonadism supports testosterone replacement for symptomatic men with confirmed low levels, though it does not specifically endorse compounded formulations over FDA-approved products [10]
For individuals with more metabolic resistance (pre-diabetes, metabolic syndrome, polycystic ovarian syndrome [PCOS]) GLP-1/GIP can have even greater effects on body weight, cardiovascular health, diabetes prevention, and overall improvement in health markers than GLP-1 alone
In that case, you should seek medical advice as soon as possible
If you are not seeing results at your current dose after six to eight weeks, discuss dose escalation with your provider at your next follow-up
Wharton S, Liu A, Pakseresht A, Nrtoft E, Haase CL, Mancini J, et al