While gastrointestinal symptoms dominate the adverse effect profile, patients and clinicians have increasingly questioned whether these medications might contribute to musculoskeletal complaints, including muscle pain, weakness, or discomfort
Slowing Gastric Emptying : By delaying the time it takes for food to leave the stomach, semaglutide increases feelings of fullness and satiety, leading to reduced food intake
Long-term use, however, may lead to changes in your weight
Pull back the plunger past your dose amount
Conversely, DKD in type 2 diabetes mellitus shows greater pathological heterogeneity, with some people developing classical glomerular lesions, while others present with atypical features such as prominent tubulointerstitial damage, vascular abnormalities, or coexisting non-DKD pathology [21,22]