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It is also approved to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease (Ozempic), and in adults with established cardiovascular disease and either obesity or overweight (Wegovy)

Monotherapy protocols are commonly initiated at 0.6 mg per week and escalated to a maximum studied dose of 4.5 mg as tolerated

It also raises questions around the physical and mental health impacts of weight cycling (losing and regaining weight in a repeated pattern)

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Avoid layering with low-pH L-ascorbic acid or strong AHA/BHA exfoliants at the same time