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The 3D structure of the GPx3 mutant with all Cys converted to Ser was refined by MD simulations and analyzed with Profile-3D and Procheck following the method as described previously 31,32

P300-mediated histone lactylation has been observed to be predominantly localized at transcription start sites, significantly driving the malignancy of the U87MG GBM cell line and promoting immunosuppression in the GBM microenvironment

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doi: 10.3389/fmicb.2016.00410 [DOI] [PMC free article] [PubMed] [Google Scholar] [56].Tsakou F, Jersie-Christensen R, Jenssen H, et al