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On the one hand, hydrogen peroxide is necessary for glucose-triggered insulin secretion, but on the other hand, pancreatic islets are abundant with hydrogen peroxide-metabolizing enzymes, including GPxs

10.3389/fnagi.2020.614650 [DOI] [PMC free article] [PubMed] [Google Scholar] 313.Mazumder S, Bindu S, De R, Debsharma S, Pramanik S, Bandyopadhyay U

Science 284 , 11431146 (1999) V

Moreover, during zinc deficiency, enzymes such as glycosyltransferases and proteases are impaired, resulting in faulty receptor trafficking, extracellular matrix disintegration and hypoglycosylated proteins, defects that underlie congenital disorders of glycosylation 137