glp-1 and gip/glp-1 receptor agonists 𝗧𝗵𝗲 𝗘𝗳𝗳𝗲𝗰𝘁 𝗼𝗳 𝗚𝗟𝗣-𝟭 𝗥𝗲𝗰𝗲𝗽𝘁𝗼𝗿 𝗔𝗴𝗼𝗻𝗶𝘀𝘁𝘀 𝗼𝗻 𝗚𝗹𝘆𝗰𝗮𝘁𝗲𝗱 𝗛𝗲𝗺𝗼𝗴𝗹𝗼𝗯𝗶𝗻 𝗟𝗲𝘃𝗲𝗹𝘀 ⁣ ⁣ Randomized, placebo-controlled trials of the glucagon-like peptide-1 (GLP-1) have provided strong Frontiers | Mechanisms of action

1,2 Initially developed as antidiabetic treatments, GLP-1 RAs and, more recently, dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists have demonstrated favourable metabolic outcomes with significant and sustainable weight loss in large randomised controlled trials (RCTs) and real-world studies

Clinical oversight required: Dosage adjustments, reconstitution, and injection technique should always be guided by a licensed provider

Theanine nasal spray GABA may help ease stress and nervous system overactivity

A variant is available with a higher peptide content GHK-Cu 50mg, and research on reducing the visibility of wrinkles uses, among others, Matrixyl 3000 (palmitoyl tripeptide) and Snap-8 (octapeptide modulating facial tension)

Garlic to Help Maintain Optimal Glutathione Levels Contrary to popular belief, dogs can eat garlic in low quantities