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In addition, ALOX15 can induce a series of destructive events when cells are subjected to glutamate-induced oxidative stress, including breakdown of the mitochondrial membrane potential, production of ROS, and cytochrome c release, finally leading to cell death (Pallast et al., 2009)

PMID: 38784519

This mechanism appears fundamental to the peptides observed neuroprotective effects across diverse neurological injury models

While your body can use those amino acids to try and rebuild glutathione, it is much less efficient than delivering the intact molecule directly to your cells