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Mice were then maintained in the declined position for an additional minute, during which stimulation was applied to the sternum region to enhance volume uptake

A phase Ib study showed that R1507 is well tolerated when added to six standard chemotherapy regiments in patients with various solid tumors, including BrCa [128]

Skin Research and Technology , 16(3), 348-354

The success of both compounds, using different combinations of the same three receptor targets, has validated the multi-agonist approach and opened the door for even more combinations