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The higher mRNA 1-adrenergic receptor expression in the PCZ group, along with a reduced myocardial IL-6 mRNA expression and myocardial injury compared to the septic control group is consistent with a cardioprotective effect, which aligns with previous observations of PCZ reducing myocardial oxidative stress in mice [20]
Altered PTEN pathway expression has been found to enhance the efficacy of anti-PD-1 and anti-CTLA-4 antibodies in mouse models 60 and to improve the chemoresistance of breast cancer cells to DOX 61
Lili Ladaga Editor Shahbandeh M
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