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These effects arise from rebalanced B-cell lymphoma 2 (Bcl-2) family signaling, which favors anti-apoptotic proteins over pro-apoptotic B-cell lymphoma-2-associated X protein (Bax)

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CAF-conditioned medium inhibited the accumulation of doxorubicin, but not taxol, in prostate cancer cells in a manner that was associated with increased cancer cell glutathione levels

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It is obvious that, owing to the increased oxidative stress and persisting inflammation in dry skin, more and more glutathione is utilized to combat these conditions