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It says GLP-1 drugs enhance secretion of intestinal hormones partly through intact bile acid signaling, so a shifted signaling environment can change efficacy, gastrointestinal side effects and metabolic response

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[DOI] [PubMed] [Google Scholar] 17.Prkacin I., Aralica G., Perovic D., Separovic J., Gjurasin M., Lovric-Bencic M., Stancic-Rokotov D., Ziger T., Anic T., Sikiric P., et al

The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting-state amygdala connectivity

The Wall Street Journal first reported the CMS guidance