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Together, these findings uncover the phosphorylation-dependent CDK11/P-SF3B1/SNIP1 signaling axis that is critical for pre-mRNA splicing and cellular proliferation and provide a mechanistic insight into its dysregulation in disease
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Also, NAC treatment increased p-IRE1 labeling, compared to the IFN-+Anta and IFN-+NAC + Anta groups (Fig
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Therefore, making ferroptosis inducers druggable for cancer therapy sounds like a promising strategy to challenge and overcome acquired resistance to other drugs
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