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Potential Benefits: A Summary Based on the available (predominantly preclinical) literature, the following potential benefits have been identified: Risks & Safety Considerations Known & Reported Side Effects Because large-scale human trials are lacking, our understanding of the side effect profile is limited
Modeling studies ( Diabetes Obes Metab 2025 Apr;27(4):2251-2258) do suggest that biweekly dosing can preserve approximately 70% of the weight loss effects seen with once weekly dosing
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells
*Correspondence: Arjola Bano, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
