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However, suppression of IRP1 by alpha-enolase (ENO1) protects hepatocellular carcinoma cells from ferroptotic cell death [25]

In a study by Jalota Badhawar et al., a TAT-SMAR1-derived chimeric peptide (p44) considerably activated p53 by phosphorylating serine 15, via activating p21 protein and inhibiting cell cycle progression [56]

A particularly fascinating aspect of reactive microglia in neurodegeneration is their dynamic receptor expression profilewhile these receptors are nearly undetectable in resting microglia, they become markedly upregulated upon activation