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If you are combining semaglutide with phentermine , berberine , or metformin , these additional medications can further affect appetite and blood sugar, making calorie monitoring even more important

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Retatrutide remains in clinical development and is not approved for general prescribing or self-administration in the UK

While Semaglutide (Ozempic, Wegovy) targets one receptor and Tirzepatide (Mounjaro, Zepbound) targets two, Retatrutide activates three distinct metabolic receptors simultaneously

Common side effects of Ozempic and Wegovy include nausea, vomiting, diarrhea, constipation, and abdominal pain