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Uetrecht J (2019) Mechanistic studies of idiosyncratic DILI: Clinical implications

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Tesofensine is primarily used to promote weight loss in individuals struggling with obesity

It bypasses digestive breakdown and can improve the bioavailability of certain compounds

Multiple psychiatric comorbidities, including attention deficit hyperactivity disorder (ADHD) as well as anxiety, personality, and eating and substance use disorders, interfere with diagnosis and treatment and likely contribute to increased disease morbidity and mortality in general and to increased suicide risk in particular ( These poor outcomes reflect our growing recognition, based on neurobiological and neuroimaging research, which bipolar disorder is frequently an aggressive and corrosive condition