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Important Note on Extreme Lightening: The primary side effect cited in medical literature is the intended effect: skin lightening

It affects most commonly the hand, wrist, and foot, but it can also affect large joints

B12 shots are considered safe for most individuals

For patients managing peripheral neuropathy, sciatica, or nerve-related pain at Connecticut Pain Solutions, B12 injections can serve as a supportive adjunct to interventional treatments like neurological testing, pain management procedures, and IV vitamin infusion therapy

CL Answer 3 Tips to Prevent Powdered Supplements from Clumping Learn more about how powdered supplements compare to capsules and if clumping is worrisome