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Smoking commonly causes pigmentation on the gums, palate, and lips, as well as other areas on the front of the body, like the face

The September 2023 label update acknowledging ileus risk came only after the FDAs own adverse event reporting system documented numerous cases, raising questions about why this warning wasnt included from the drugs initial approval

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Melanomas are malignant tumors originating from melanocytes in the epidermis basal layer

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