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9% vs placebo, with effects on both fasting and postprandial glucose Cardiometabolic Improvement: Decreases in blood pressure, waist circumference, lipid fractions, and inflammatory biomarkers

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This glucose-dependent mechanism is fundamentally different from older diabetes medications like sulfonylureas, which stimulate insulin regardless of blood sugar levels and carry a significant risk of hypoglycemia

Subsequent oxidative stress damages cellular DNA and organelles, activating repair processes that inadvertently divert glucose metabolism toward harmful pathways [24]