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Topiramate (Topamax): introduction of new safety measures including a Pregnancy Prevention Programme

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Heilig CW, Saunders T, Brosius FC 3rd, Moley K, Heilig K, Baggs R, Guo L, Conner D (2003) Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy

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In adipocytes, NNMT inhibition elevates NAD and SAM and suppresses de novo lipogenesis in a concentration-dependent manner, consistent with on-target activity [13]

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