These unique properties position copper as a specialized redox messenger capable of mediating compartmentalized signaling pathways that are inaccessible to iron or zinc (216,217)
J Biol Chem 255:107112 Singh RH (2007) Nutritional management of patients with urea cycle disorders
Pate KT, Stringari C, Sprowl-Tanio S, Wang K, TeSlaa T, Hoverter NP, et al
Recalls & Warnings December 08, 2015 Non-Decolorized Aloe, Goldenseal Root Added to Prop 65 List of Cancer-Causing Chemicals On December 4, 2015, California's Office of Environmental Health Hazard Assessment (OEHHA) added non-decolorized whole leaf extract of aloe vera and goldenseal root powder to the state's list of chemicals known to cause cancer - part of the Safe Drinking Water and Toxic Enforcement
It is activated by voltage-dependent Ca 2+ -channels, as well as neurotransmitter and hormone receptors, that increase intracellular Ca 2+ and cause accumulation of the Ca 2+ -calmodulin complex