5.2 Mitochondrial stability and antioxidant effects Although the effects of omega-3 PUFAs on ROS production within mitochondria have yielded mixed results, omega-3 PUFAs are known to influence mitochondrial function in several ways, including impacts on membrane potential, respiration rates, the activity of mitochondrial complexes, and ROS production
[44] Henning SM, Wang P, Heber D
An example of this that is currently being investigated by the medical community is the connection between MTHFR mutations and resulting changes in downstream pathways that result in the body reading genes that are not normally read
This effect was evidenced by alterations in total and ferrous iron levels in the hippocampus and an increase in the expression of PEBP1, ERK1/2, and key ferroptosis-related proteins, including GPX4, FTH1, ACSL4, and COX2 (Jiao et al., 2021)
The residue (dry extract) is suspended in 2 mL of 96% ethanol and the total volume in the volumetric flask increased to 100 mL by adding distilled water