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When antibiotics, particularly sulphur drugs, are used for extended periods, the normal synthesis of Folic acid in the gut will be reduced and the requirements for Folic Acid are increased.

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When patients begin weight loss treatment, multiple physiological changes occur simultaneously, and symptoms may arise from the weight loss process itself, dietary changes, increased physical activity, or coincidental factors rather than the medication directly

Funds were used to cover expenses related to the data extraction and statistical analysis of the meta-analysis