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Mol Endocrinol (1988) 2:8715

It activates the expression of inflammatory signaling pathways through both direct contact with immune cell surface receptors and internalization by immune cells, inducing immune cell activation and promoting inflammatory responses ( Although sUA and MSU have had opposite regulatory effects on immune cells in some studies, both have been known to impact on immune cells

Kumar, C

Safety and Observed Side Effects While generally well-tolerated, Retatrutides clinical trials indicated some common side effects, including mild-to-moderate nausea, diarrhea, vomiting, and constipation, typically linked to dose increases