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DOI : 10.1016/j.jff.2024.106108

Proteostasis resilience: a new framework for disease intervention Across disease systems, one recurring theme emerges: the difference between cellular survival and failure is determined not only by the existence of proteostasis pathways but also by their resilience capacity and their ability to respond robustly, flexibly, and coordinately

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CAV-1 reduction induces Janus kinase (JAK)/STAT pathway activation in psoriatic inflammation, leading to further keratinocyte proliferation and cytokine/chemokine production