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The following critical factors helped us to select our top picks: Bioavailability: How B12 can be consumed and utilized by the body

These second messengers, particularly cAMP, may activate protein kinases, enzymes considered responsible for phosphorylating target proteins

Research has shown that individuals with low levels of Vitamin B12 are more likely to experience symptoms of depression and anxiety

I mentioned previously that the symptoms of B12 deficiency can mimic hypothyroid symptoms which can make the diagnosis hard to spot

Vitamin B12 is part of the vitamin B-complex range, which is a class of water-soluble vitamins essential for cell growth and development