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Decreased levels of carnosine seen in our study in both ME/CFS and long COVID may contribute to patients experience of muscle fatigue, which has been previously associated with acidosis [79]

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Zinc Supplementation Modulates NETs Release and Neutrophils' Degranulation

Targeting inflammasome activation, inhibiting caspase-1, employing anti-inflammatory agents, and modulating the gut microbiota and bile acid metabolism represent promising avenues for developing novel treatments for this common and potentially life-threatening condition