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For a substance or method to be added to the List, it must be determined that it meets at least two of the following three criteria: It has the potential to enhance or enhances sport performance It represents an actual or potential health risk to the athletes It violates the spirit of sport The List is released three months ahead of it taking effect so that athletes, their entourage and other stakeholders can acquaint themselves with any modifications

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Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR