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However, it is a quite invasive technique, and there is still a lot of uncertainty about the uptake by the brain, which might depend on brain states (e.g., awake vs anesthetized), the hydrophobicity of the compound, or its interaction with efflux transporters (Abbott et al., 2018)

That's why this confusion persists in practices for months, sometimes years, before anyone traces it back to the 90471 vs 96372 distinction

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However, the use of synthetic growth hormone comes with several drawbacks