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Next, when DPCs were treated with the -catenin inhibitor MSAB (5 M), the results showed that co-culture with MSCs reversed the DHT-induced downregulation of -catenin and Myc expression, and also inhibited the expression of GSK3 (Fig

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On the other hand, DCs may also play a prominent role in the establishment of viral latency by increasing the amount of LAT in the TGs of mice ( ex vivo with Flt3L, or GM-CSF, and then transferred into recipient mice displayed increased the LAT expression in the TGs, a process associated with lymphoid-related DCs (CD11c + CD8 + ) ( Immune soluble factors have also been shown to modulate HSV-1 latency in neurons

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