Curcumin contributes to maintaining metabolic functions, while Gotu Kola is included for its involvement in cellular processes
All these parameters need to be normal before initiating the treatment
9,10 The culmination of these signaling events is oncotic necrosis 11 rather than apoptosis, 12 despite some overlap in mechanisms, such as the translocation of Bax and Bid to the mitochondria, 1315 mitochondrial cytochrome c release, 13,14,16 and DNA fragmentation, as indicated by DNA ladder formation 17,18 and TUNEL staining
Parker, V
It may also include kojic acid, azelaic acid, and antioxidant protection in the form of resveratrol and green tea extract to supplement the effects of hydroquinone