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Its mechanism of action is not fully known, although, in addition to the known insulin-sensitizing effect on the liver and muscle, it also appears to have an anorectic effect: central to the hypothalamic-pituitary circuits and peripheral due to increased secretion of GLP-1 from the intestine [75]
GLP-1(2836) modulates sAC by increasing intracellular ATP levels, with accompanying cAMP accumulation lost in sAC / cells
Specifically, gravid adult glp-1(bn18) hermaphrodites were transferred to each feeding RNAi plate, and the germline phenotypes of progeny were examined by DAPI staining when they became adults (3 days after L1) (Fig
Basit H, Tan ML, Webster DR
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