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Mice studies do show that they live longer when given supplemental melatonin over the course of their lives, starting in adulthood.[ref][ref][ref][ref] Animal studies also show that melatonin supplementation (beginning in middle to old age) prevents the decrease in bone mass associated with aging.[ref] It also increases mitochondrial function.[ref] Melatonin is necessary to reap the benefits of exercise when aging.[ref] Supplemental melatonin also doubles insulin sensitivity in older animals.[ref] We dont do human studies on chronic calorie restriction to extend lifespan nor have there been long-term studies in humans on supplemental melatonin for fifty-plus years to know the effect

Specifically, it slows down activity at the NMDA receptor, one of the three glutamate receptors

If you need more than just Total Glutathione lab test - add more tests one by one

As you increase your dose, if you find that you cannot tolerate your side effects, you should stay on the same dose for 2 continuous weeks