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As people reach early adulthood the thymus starts to slowly decrease in activity

IV Administration: Rapid intravenous (IV) infusion can cause temporary discomfort, including a metallic taste, flushing, or transient nausea

EGF at roughly 6,000 Da, PDRN as a polymeric mixture, and hyaluronic acid above 50 kDa cannot

Practice Bulletin, 196, 1-18

Reported side effects are generally mild and may include: Redness, swelling, or discomfort at the injection site Mild headache Fatigue (usually short-lived) Minor and transient changes in blood sugar (rare) AOD-9604 does not appear to cause the joint pain, fluid retention, or glucose dysregulation commonly seen with full hGH therapy