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Research demonstrates that 5-Amino-1MQ exhibits high selectivity for NNMT and does not inhibit structurally related methyltransferases or other enzymes in the NAD+ biosynthesis pathway, including NAMPT and SIRT1

(8) These findings underline the complex and multifaceted ways in which DSIP might influence sleep and stress management, although more research is needed to understand its mechanisms of action

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Psychopharmacology, 185 (1), 93-103

Murgia F, Angioni S, DAlterio MN, Pirarba S, Noto A, Santoru ML, et al