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Using a Western blot assay, a study found a significantly higher level of 4-HNE protein adducts (4-HNE PAs) in the plasma of children with ASD (221)

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Ethosuximide, approved in 1958, replaced it

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This decline can be detected using fluorescent dyes such as TMRM or JC-1, which show a decrease in fluorescence when mitochondrial potential drops