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Sometimes even activities of daily living such as going up and down stairs or getting in and out of cars may produce pain in a knee with a torn meniscus

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The biggest concern we have from a medical standpoint is that patients who lose weight quickly and without significantly changing their lifestyle are prone to gaining more weight once they stop the drug

There have also been theoretical concerns regarding a possible increased risk of DKA with GLP-1 agonist use in type 1 diabetes