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Phase III trial that led to the approval of Tirzepatide for weight management in patients with obesity

Physicochemical properties: As a small peptide, BPC157 exhibits peptide-like properties susceptibility to proteolytic degradation in biological fluids, potential for rapid renal clearance when systemically administered, and a molecular mass on the order expected for a short (15 amino acid) peptide (i.e., low kilodalton range)

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doi: 10.1016/j.neurobiolaging.2016.03.005 13 CristofanoA.SapereN.La MarcaG.AngiolilloA.VitaleM.CorbiG.et al

Other reports document successful metabolic reprogramming of antibiotic-resistant pathogenic bacteria 26,55,56