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Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial

Following multiple doses, mean insulin-like growth factor (IGF-1) levels remained above baseline for up to 28 days

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Trube G, Rorsman P, Ohno-Shosaku T

The metabolically stabilized 6-AH family member, D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 , had a t| /2 in blood of 80 min compared to the parent compound Norleual (Nle-Tyr-Leu-T-(CH 2 -N) 3 -His-Pro-Phe, SEQ ID NO: 1), which had a tj 2 in blood of Cm ax concentration in plasma extrapolated to time zero (Co), terminal elimination half-life (ti 2 ), volume of distribution (Vd), and clearance (CL)