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Transcranial PBM (tPBM): Waking the Dormant Mechanism: Red and Near-Infrared (NIR) light (810nm) penetrates the skull and is absorbed by Cytochrome C Oxidase in the mitochondria

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The window for market entry remains open partly due to persistent supply constraints among current manufacturers and partly because the addressable patient population continues expanding as clinical evidence mounts for GLP-1 benefits across obesity, diabetes, MASH, cardiovascular disease, and other indications

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The peptide primarily activates melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R, with particular affinity for MC3R and MC4R at therapeutic doses