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By reducing appetite and slowing digestion, these medications help patients feel satisfied after meals, making it easier to consume fewer calories without feeling deprived

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Assuming that the treatment reduces the mean change of [ 18 F]FDG SUV in the participants with Alzheimers disease to 0.025 (44% effect size), 82 participants would be required per group to provide 80% power at a 5% significance level

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