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GLP-1 therapies are not recommended in people with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2 (MEN2)

In the STEP 1 clinical trial published in the New England Journal of Medicine, patients using semaglutide 2.4 mg once weekly lost an average of 14.9% of their body weight over 68 weeks, with over 50% of participants achieving at least 15% weight loss

These HLA types are common found in over a quarter of the population

WIth Type 2 Diabetes, problems can occur when beta cells dont function properly

Second step: two of the authors (DLP and JAVRV) evaluated, synthesized, and coded the information into the various topics